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Methylation at lysine 4 of histone H3 in ecdysone-dependent development of Drosophila

✍ Scribed by Sedkov, Yurii; Cho, Elizabeth; Petruk, Svetlana; Cherbas, Lucy; Smith, Sheryl T.; Jones, Richard S.; Cherbas, Peter; Canaani, Eli; Jaynes, James B.; Mazo, Alexander


Book ID
109892469
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
430 KB
Volume
426
Category
Article
ISSN
0028-0836

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## Abstract Epigenetic alterations play an important role in carcinogenesis. Recent studies suggested that global histone modifications are predictors of cancer recurrence in various tumor entities. Our study was performed to evaluate histone H3 lysine 4 mono‐methyl (H3K4me1), ‐di‐methyl (H3K4me2)