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Methyl Transfer from Methylcobaloxime to (Triphos)Ni(PPh 3 ): Relevance to the Mechanism of Acetyl Coenzyme A Synthase

✍ Scribed by Eckert, Nathan A.; Dougherty, William G.; Yap, Glenn P. A.; Riordan, Charles G.


Book ID
125968370
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
67 KB
Volume
129
Category
Article
ISSN
0002-7863

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The catalytic system PdCI,(PPh,),-HCI is highly active and selective in the hydrogen transfer reaction from H,O-CO to PhCOCH,CHOHCOOH which yields the corresponding y-keto acid PhCOCH,CH,COOH, with concomitant evolution of C02. An increase of temperature, pressure of carbon monoxide and catalyst con