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Methyl phosphonate as a 31P-NMR probe for intracellular pH measurements in Dictyostelium amoebae

✍ Scribed by Satre, Michel; Martin, Jean-Baptiste; Klein, Gérald

Book ID: 121897928
Publisher: Elsevier Science
Year: 1989
Tongue: English
Weight: 647 KB
Volume: 71
Category: Article
ISSN: 0300-9084
DOI: 10.1016/0300-9084(89)90076-X

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## Abstract Uncertainty regarding the intracellular/extracellular distribution of inorganic phosphate (__P__~i~) in tumors has raised concerns that pH calculated from the tumor __P__~i~ chemical shift may not accurately represent the intracellular pH (pH~in~). This issue was addressed in subcutaneo