Methyl 1-tert-butyl-4-(hydroxydiphenylmethyl)-2-oxopyrrolidine-3-carboxylate
✍ Scribed by Yu, Jin-Di ;Lian, Gao-Yan ;Zhang, Dan-Wei ;Wang, Jing-Mei ;Chen, Min-Qin
- Publisher
- International Union of Crystallography
- Year
- 2007
- Tongue
- English
- Weight
- 263 KB
- Volume
- 63
- Category
- Article
- ISSN
- 1600-5368
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✦ Synopsis
In the title compound, C 23 H 27 NO 4 , the -lactam ring adopts an envelope conformation. An O-HÁ Á ÁO hydrogen bond links the molecules into a chain which runs parallel to the c axis.
📜 SIMILAR VOLUMES
Single-crystal X-ray study T = 123 K Mean '(C±C) = 0.002 A Ê R factor = 0.038 wR factor = 0.104 Data-to-parameter ratio = 21.9 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.
The title compound, C 27 H 39 N 3 O 9 , is a key intermediate in the synthesis of novel -turn mimetics based on electrophilic amination of enantiomerically pure (S)-pyroglutamic acid. The molecule adopts an extended conformation which is not stabilized by either intra-or intermolecular hydrogen bond
In the solid state, the title compound, C 15 H 23 NO 4 , forms centrosymmetric dimers in which individual molecules are linked by intermolecular N-HÁ Á ÁO hydrogen bonds. The pyrrole ring is planar within 0.004 (9) A ˚.