## Background: This study was undertaken to determine whether the use of intermediate dose methotrexate in combination with vinblastine, doxorubicin, and cisplatin as first-line therapy increases the proportion of major responders and overall survival in patients with unresectable or metastatic tra
โฆ LIBER โฆ
Methotrexate, vinblastine, doxorubicin and cisplatin combination regimen as salvage chemotherapy for patients with advanced or metastatic transitional cell carcinoma after failure of gemcitabine and cisplatin chemotherapy
โ Scribed by Han, K S; Joung, J Y; Kim, T S; Jeong, I G; Seo, H K; Chung, J; Lee, K H
- Book ID
- 109999351
- Publisher
- Nature Publishing Group
- Year
- 2007
- Tongue
- English
- Weight
- 103 KB
- Volume
- 98
- Category
- Article
- ISSN
- 0007-0920
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## Abstract ## BACKGROUND Platinumโbased regimens have improved response rates and survival in patients with advanced transitional cell carcinoma (TCC) of the urothelial tract. However, the toxicities of platinumโbased chemotherapy are considerable. Regimens with reduced toxicity that are applicab