Methotrexate plus L-asparaginase. An active combination for children with acute nonlymphocytic leukemia
โ Scribed by Melissa M. Hudson; Gary V. Dahl; David K. Kalwinsky; Ching-Hon Pui
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 390 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The Childrens Cancer Study Group conducted four therapeutic studies on a total of 1006 children with acute nonlymphocytic leukemia from 1972 to 1983. This report describes the therapeutic strategies of these studies and examines trends in induction rates and long-term outcome over this period. The r
## Abstract A novel assay for the determination of lโasparaginase activity in human plasma is described that is based on the HPLC quantitation of lโaspartic acid produced during enzyme incubation. Methods for monitoring lโasparagine depletion are also described. Chromatography of lโaspartic acid, l