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Methotrexate injury induces increased expression of cyclooxygenase-2 and prostaglandins in intestinal epithelial cells

✍ Scribed by Huang, Frederick S.; Ye, Yumei; Marquart, Felicitas L.; Chung, Dai H.; Evers, B. Mark

Book ID
121998995
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
259 KB
Volume
124
Category
Article
ISSN
0016-5085

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## Abstract Inflammatory bowel diseases (IBD) are linked to an increased risk of developing colon cancer, by inflammatory mediators and alterations to the extracellular matrix (ECM). The events induced by inflammatory mediators lead to dysregulated activation and induction of inflammatory genes suc