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Methotrexate Conjugates: A Molecular In Vivo Protein Tag

✍ Scribed by Lawrence W. Miller; Julia Sable; Philip Goelet; Michael P. Sheetz; Virginia W. Cornish


Book ID
101560218
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
139 KB
Volume
43
Category
Article
ISSN
0044-8249

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Methotrexate covalently bound to human serum albumin in a 1:1 molar ratio (MTX-HSA) is a new macromolecular drug which is currently being studied in phase I clinical trials by the German Association for Medical Oncology (AIO) Phase I/II study group. Previous studies have shown that MTX-HSA differs f