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Methods of minimal residual disease (MRD) detection in childhood haematological malignancies

✍ Scribed by Justyna Jółkowska; Katarzyna Derwich; Małgorzata Dawidowska

Publisher
Springer-Verlag
Year
2007
Tongue
English
Weight
82 KB
Volume
48
Category
Article
ISSN
1234-1983

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Patients with acute leukemia in clinical remission may still have up to 10 10 residual malignant cells (the upper limit of detection by standard morphologic techniques). Sensitive techniques to detect minimal residual disease (MRD) may allow better estimates of the leukemia burden and help the selec