Explores The Role Of Cytokines In Immunotoxicology And Human Health On A Number Of Levels Ranging From Basic Research To Highly Applied Therapeutic Applications. The First Section Of The Book Is Devoted To Basic Concepts Of Cytokine Biology, Especially As This Relates To The Practice Of Immunotoxicology. The Second Section Of The Book Describes How Cytokines Are Important To Human Health And Disease, And Provides Practical Approaches For Assessing The Role Of Cytokines In These States. In The Third And Final Section Of The Book, The Increasingly Important Use Of Cytokines As Therapeutics Is Explored In Detail. Introduction To Cytokines As Targets For Immunomodulation / Theresa L. Whiteside -- Cytokine Measurement Tools For Immunotoxicology / Rob J. Vandebriel -- The Relevance Of The T1/t2 Paradigm In Immunotoxicology: Example Of Drug Hypersensitivity Reactions / HervΓ© Lebrec And John Vasilakos -- Microbial Exploitation And Subversion Of The Human Chemokine Network / James E. Pease -- The Use Of Cytokines In The Identification And Characterization Of Chemical Allergens / Rebecca J. Dearman And Ian Kimber -- Inflammatory Cytokines And Lung Toxicity / Debra L. Laskin ... [et Al.] -- Cytokine Polymorphisms And Relationship To Disease / Berran Yucesoy ... [et Al.]. Effects Of Drugs Of Abuse On Cytokine Responses / Stephen B. Pruett -- Preclinical Approaches For Safety Assessment Of Cytokines / Peter T. Thomas And Melissa S. Beck-westermeyer -- Flu-like Syndrome And Cytokines / Jacques Descotes And Thierry Vial -- Cytokine-induced Vascular Leak Syndrome / Roxana G. Baluna -- Cytokines And Autoimmune Diseases: From The Control Of Autoimmune Diseases With Anti-cytokine Treatment To The Induction Of Autoimmunity With Cytokine Treatment / Pierre Miossec -- Evaluation Of Antibodies In Clinical Trials Of Cytokines / Steven Swanson -- Cytokines And Pharmacokinetic Drug Interactions / Kenneth W. Renton. Evaluation Of The Immunological Effects Of Cytokines Administered To Patients With Cancer / Michael J. Robertson -- Clinical Adverse Effects Of Cytokines On The Immune System / Thierry Vial And Jacques Descotes. Edited By Robert V. House, Jacques Descotes. Includes Bibliographical References And Index.