[Methods in Molecular Biology] DNA Repair Protocols Volume 314 || Quantitative PCR-Based Measurement of Nuclear and Mitochondrial DNA Damage and Repair in Mammalian Cells

Measurement of DNA damage and repair in

Measurement of DNA damage and repair in the λLIZ transgene in a Big Blue® rat cell line by quantitative PCR

✍ Haiyan Yang; Gopaul P. Kotturi; Johan G. de Boer; Barry W. Glickman 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 112 KB 👁 1 views

DNA damage and its subsequent repair occur heterogeneously throughout the genome, which reflects the nature of the damaging agents, gross chromosomal structure, the specific nucleotide sequence, and transcriptional status. We selected to investigate the repair of DNA damage in an artificial, transge