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Methods for the Detection of Non-Random Base Substitution in Virus Genes: Models of Synonymous Nucleotide Substitution in Picornavirus Genes

โœ Scribed by Daniel Haydon; Nick Knowles; John McCauley

Book ID
110257529
Publisher
Springer
Year
1998
Tongue
English
Weight
191 KB
Volume
16
Category
Article
ISSN
0920-8569

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The CDKff2 gene, encoding the cyclin-dependent kinase inhibitor p16. is a tumour suppressor gene that maps to chromosome band 9p2 I -p22. The most common mechanism o f inactivation of this gene in human cancers is through homorygous deletion; however, in a smaller proportion of tumours and tumour ce