Methods for Structure Elucidation by High-Resolution NMR Applications to Organic Molecules of Moderate Molecular Weight

✍ Scribed by Gy. Batta, K.E. Kövér and Cs. Szántay (Eds.)

• Publisher: Elsevier Science
• Year: 1997
• Tongue: English
• Leaves: 369
• Series: Analytical Spectroscopy Library 8
• Edition: 1
• Category: Library

✦ Synopsis

Nuclear Magnetic Resonance Spectroscopy (NMR) is now widely regarded as having evolved into a subscience. The field has become immensely diverse, ranging from medical use through solid state NMR to liquid state applications, with countless books and scientific journals devoted to these topics. Theoretical as well as experimental advance continues to be rapid, and has in fact accelerated by many novel innovations. This multi-authored book focuses on the latest developments in the rapidly evolving field of high resolution NMR, specifically with a view to applications on the structure elucidation of organic molecules of moderate molecular weight. Conceptually it differs from basic educational texts, hard-core scientific papers and regular review articles in that each chapter may be regarded as the authors' personal account of their special insights and results that crystallised after several years of research into a given topic. The book revolves around several themes and offers a handful of scientific "gems" of various colors, reflecting the great diversity of NMR. It contains 16 loosely connected chapters written by some of today's most accomplished NMR scientists in the world. Each chapter is a unique synthesis of the authors' previous research results in the given field, and thus projects special insights. Much emphasis has been given to the latest developments in NMR, in particular to selective pulses and pulsed field gradients. As a part of the series "Analytical Spectroscopy Library", with subsequent editions coming along this book should provide a platform for future research accounts of similar flavor. The material is presented in a mostly non-mathematical fashion, and isintended mainly for chemists, application NMR scientists and students with already some background in NMR. Some of the chapters slightly overlap in the discussed topics, which is particularly exciting in terms of gaining insight into the same area from different angles.

✦ Table of Contents

Content:
Preface
Page v

List of contributors
Pages ix-x

Chapter 1 Selective pulses in NMR Original Research Article
Pages 1-17
Sébastien J.F. Vincent, Catherine Zwahlen

Chapter 2 Multiple selective excitation: A method to improve the efficiency of selective 1D and 2D experiments Original Research Article
Pages 19-49
Peter Bigler

Chapter 3 Concatenation of polarization transfer steps in 1D homonuclear chemical shift correlated experiments. Application to oligo- and polysaccharides Original Research Article
Pages 51-89
Dušan Uhrín

Chapter 4 The selective reverse INEPT experiment Original Research Article
Pages 91-105
Gareth A. Morris, Ian C. Clements

Chapter 5 Groesy, gradient-enhanced selective 1D roe measurements Original Research Article
Pages 107-119
Pere Adell, Teodor Parella, Francisco Sánchez-Ferrando, Albert Virgili

Chapter 6 The DANTE-Z experiment Original Research Article
Pages 121-129
D. Canet, C. Roumestand

Chapter 7 One-dimensional TOCSY and related 1D techniques Original Research Article
Pages 131-147
Tuck C. Wong

Chapter 8 Use of high power spin-lock purge pulses in high resolution NMR spectroscopy Original Research Article
Pages 149-171
Gottfried Otting

Chapter 9 Decoupled HMBC (D-HMBC), an improved version of HMBC Original Research Article
Pages 173-185
Haruo Seto, Kazuo Furihata

Chapter 10 Optimal acquisition and presentation of HoMQC spectra Original Research Article
Pages 187-207
István Pelczer, Karl D. Bishop

Chapter 11 High resolution diffusion ordered spectroscopy Original Research Article
Pages 209-226
Gareth A. Morris, Hervé Barjat

Chapter 12 Chemical exchange measurements in NMR Original Research Article
Pages 227-263
Alex D. Bain, G.J. Duns

Chapter 13 Homonuclear two-dimensional cross-relaxation spectroscopy Original Research Article
Pages 265-302
Nenad Juranić, Zsolt Zolnai, Slobodan Macura

Chapter 14 Reference deconvolution Original Research Article
Pages 303-316
Gareth A. Morris, Hervé Barjat

Chapter 15 The super fast inversion recovery (SUFIR) experiment Original Research Article
Pages 317-323
D. Canet, P. Mutzenhardt, J.-B. Robert

Chapter 16 Measurements of relaxation rates for low natural abundance l=1/2 nuclei Original Research Article
Pages 325-347
Jozef Kowalewski, Lena Mäler

Subject index
Pages 349-357