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Methods for siRNA-mediated Reduction of mRNA and Protein Expression in Human Placental Explants, Isolated Primary Cells and Cell Lines

✍ Scribed by K. Forbes; M. Desforges; R. Garside; J.D. Aplin; M. Westwood

Book ID
113854386
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
621 KB
Volume
30
Category
Article
ISSN
0143-4004

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## Abstract The purpose of this study was to investigate the correlation between mRNA and protein levels for P‐glycoprotein (P‐gp) expressed in various cell lines to validate the estimation of P‐gp activity from its mRNA levels. P‐gp expression levels in various cell monolayers, normal, P‐gp‐induce