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Methods for Detection of Parent-of-Origin Effects in Genetic Studies of Case-Parents Triads

✍ Scribed by Clarice R. Weinberg

Book ID: 117852899
Publisher: American Society of Human Genetics
Year: 1999
Tongue: English
Weight: 90 KB
Volume: 65
Category: Article
ISSN: 0002-9297
DOI: 10.1086/302466

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## Abstract Estimation and testing of genetic effects (genotype relative risks) are often performed conditionally on parental genotypes, using data from case‐parent trios. This strategy avoids having to estimate nuisance parameters such as parental mating type frequencies, and also avoids generatin