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Methods for Detecting Associations with Rare Variants for Common Diseases: Application to Analysis of Sequence Data

✍ Scribed by Bingshan Li; Suzanne M. Leal

Book ID
113422505
Publisher
American Society of Human Genetics
Year
2008
Tongue
English
Weight
227 KB
Volume
83
Category
Article
ISSN
0002-9297

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## Abstract A combination of common and rare variants is thought to contribute to genetic susceptibility to complex diseases. Recently, next‐generation sequencers have greatly lowered sequencing costs, providing an opportunity to identify rare disease variants in large genetic epidemiology studies.