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Methods for detecting apoptosis in thyroid diseases

โœ Scribed by R. Mirakian; K. Nye; F.F. Palazzo; A.W. Goode; L.J. Hammond

Book ID
114051016
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
282 KB
Volume
265
Category
Article
ISSN
0022-1759

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The elimination of autoreactive T cells in the thymus involves the process of programmed cell death. Animal model studies, using the lpr and gld strains of mice, have identified FAS receptor (FAS) and FAS ligand (FAS-L) as important components of this mechanism. Whether FAS and FAS-L are also implic