[Methods and Principles in Medicinal Chemistry] Voltage-Gated Ion Channels as Drug Targets (TRIGGLE: VOLTAGE-GATED ION CHANNELS AS DRUG TARGETS O-BK) || Overview of Voltage-gated Calcium Channels

✍ Scribed by Triggle, David J.; Gopalakrishnan, Murali; Rampe, David; Zheng, Wei

• Book ID: 121180778
• Publisher: Wiley
• Year: 2006
• Tongue: German
• Weight: 198 KB
• Edition: 1
• Category: Article
• ISBN: 3527312587
• DOI: 10.1002/3527608141.ch5a

✦ Synopsis

Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology.

After an introduction to the topic, the authors evaluate the structure and function of ion channels, as well as related drug interaction. A section on assay technologies is followed by a section each on calcium, sodium and potassium channels. Further chapters cover genetic and acquired channelopathies, before the book closes with a look at safety issues in ion channel drug development.

For medicinal and pharmaceutical chemists, biochemists, molecular biologists and those working in the pharmaceutical industry.