✦ LIBER ✦

Methods and applications of genetic analysis in the study of cardiovascular disease: A summary of contributions to GAW8

✍ Scribed by Dr. Alexander F. Wilson

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 690 KB
Volume: 10
Category: Article
ISSN: 0741-0395
DOI: 10.1002/gepi.1370100629

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The analyses of data provided for the cardiovascular disease section of Genetic Analysis Workshop 8 are briefly summarized. Methods using twin, segregation, and linkage analyses are used to determine, characterize, and localize genetic components involved in the etiology of cardiovascular disease and to explore the interaction of these components with known environmental risk factors. © 1993 Wiley‐Liss, Inc.

📜 SIMILAR VOLUMES

Genetic analysis of Alzheimer's disease:

Genetic analysis of Alzheimer's disease: A summary of contributions to GAW8

✍ Dr. Ellen M. Wijsman 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 809 KB

Participants in the Alzheimer's disease component of GAW8 had access to three collections of pedigrees, complete with marker data from chromosomes 19 and 21. There were a total of 94 independent pedigrees and more than 2,000 individuals. Onset of the disorder varied widely among pedigrees. These dat

Model selection and Bayesian methods in

Model selection and Bayesian methods in statistical genetics: Summary of Group 11 contributions to Genetic Analysis Workshop 15

✍ Michael D. Swartz; Duncan C. Thomas; E. Warwick Daw 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 133 KB

The research presented in group 11 of the Genetic Analysis Workshop 15 (GAW15) falls into two major themes: Model selection approaches for gene mapping (both Bayesian and Frequentist); and other Bayesian methods. These methods either allow relaxation of some of the common assumptions, such as mode o

Data Mining and Computationally intensiv

Data Mining and Computationally intensive methods: Summary of Group 7 contributions to Genetic Analysis Workshop 13

✍ Tracy J. Costello; Catherine T. Falk; Kenny Q. Ye 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 85 KB

The Framingham Heart Study data, as well as a related simulated data set, were generously provided to the participants of the Genetic Analysis Workshop 13 in order that newly developed and emerging statistical methodologies could be tested on that well-characterized data set. The impetus driving the

A genetic analysis of cardiovascular dis

A genetic analysis of cardiovascular disease risk factor clustering in adult female twins

✍ Dr. M. Mosteller 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 316 KB

Risk factors for cardiovascular disease have been shown to cluster in adult populations of men and women [Criqui et al., 19801. In a population of adult female twin pairs (ages 18-85), body mass index, systolic and diastolic blood pressure, and high and low density lipoprotein levels were found to e

Genetic contributions to quantitative li

Genetic contributions to quantitative lipoprotein traits associated with coronary artery disease: Analysis of a large pedigree from the Bogalusa heart study

✍ Heiba, Ibrahim M. ;DeMeester, Cynthia A. ;Xia, Yu-Rong ;Diep, Anh ;George, Vargh 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 1010 KB

A statistical test for detection of ance

A statistical test for detection of ancestral genetic contributions to disease occurrence in finite populations

✍ Dr. Walter W. Hauck; Alice O. Martin; D. C. Rao 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 English ⚖ 862 KB

We have been investigating cancer patterns in the Hutterites, a religious isolate residing on cominunal farms [Martin et al, 1980a,b,c]. Advantages of this population include extensive and accurate genealogies, essentially complete case ascertainment, and relatively uniform environmental background