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Methodological issues in detecting gene-gene interactions in breast cancer susceptibility: a population-based study in Ontario

✍ Scribed by Laurent Briollais; Yuanyuan Wang; Isaac Rajendram; Venus Onay; Ellen Shi; Julia Knight; Hilmi Ozcelik


Book ID
115021917
Publisher
BioMed Central
Year
2007
Tongue
English
Weight
409 KB
Volume
5
Category
Article
ISSN
1741-7015

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We used data from a population based series of breast cancer patients to investigate the genetic models that can best explain familial breast cancer not due to the BRCA1 and BRCA2 genes. The data set consisted of 1,484 women diagnosed with breast cancer under age 55 registered in the East Anglia Can