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Methodological aspects of current problems in target-based anticancer drug development

✍ Scribed by Takeharu Yamanaka; Tatsuro Okamoto; Yukito Ichinose; Shinya Oda; Yoshihiko Maehara


Publisher
Springer
Year
2006
Tongue
English
Weight
273 KB
Volume
11
Category
Article
ISSN
1341-9625

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## Abstract Survival of patients with advanced solid tumors has not significantly improved over the past 30 years. Although molecularly targeted anticancer drugs offer promise, few drugs make it through the end of the Food and Drug Administration approval process. Animal models that more closely re