Methodologic challenges in studying risk factors for progression of knee osteoarthritis
β Scribed by Yuqing Zhang; Jingbo Niu; David T. Felson; Hyon K. Choi; Michael Nevitt; Tuhina Neogi
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2010
- Tongue
- English
- Weight
- 81 KB
- Volume
- 62
- Category
- Article
- ISSN
- 2151-464X
No coin nor oath required. For personal study only.
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## Abstract ## Objective To provide an overview of prognostic factors of knee osteoarthritis (OA) progression. ## Methods We searched Medline and Embase up to December 2003 according to a specified search strategy (keywords for disease, location, and study design). Studies that fulfilled predefi
## Abstract ## Objective Osteoarthritis (OA), characterized by lateβonset degeneration of articular cartilage, is recognized to have a genetic component. We examined the role of 26 singleβnucleotide polymorphisms (SNPs) from 24 candidate genes in OA susceptibility and progression. ## Methods We