✦ LIBER ✦
Method for sequential staining of GTL-banded metaphases with fluorescent-labeled chromosome-specific paint probes
✍ Scribed by Jalal, Syed M. ;Law, Mark E. ;Christensen, Eric R. ;Spurbeck, Jack L. ;Dewald, Gordon W.
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 649 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0148-7299
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✦ Synopsis
We describe a method for use of fluorescent-labeled whole chromosome-specific paint probes on GTL-banded metaphases to utilize the combined potential of these techniques for defining chromosome abnormalities. The efficacy of this method was tested on 6 cases involving Merent chromosome abnormalities and various tissues, including blood, amniotic fluid, skin fibroblasts, and bone marrow.