✦ LIBER ✦
Methamphetamine's effect on repeated acquisitions with serial discrimination reversals
✍ Scribed by William H. Calhoun; Elisabeth A. Jones
- Publisher
- Springer
- Year
- 1974
- Tongue
- English
- Weight
- 319 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0033-3158
No coin nor oath required. For personal study only.
✦ Synopsis
Rats were trained through a series of discrimination reversals until they developed a stable, repeated acquisition baseline. Mcthamphetamine (0.5 mg/kg) accelerated acquisition measured from this baseline. The drug effect was demonstrated with successive cumulative records and with a graphic method using a distribution of error scores to develop a baseline. Generally, with low doses(0.25--0.50), methamphetamine reduced errors without affecting rewarded responding. This effect is dose dependent, although at 1.0 mg/kg the drug may disrupt operant behavior.