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Methamphetamine-induced hyperthermia and lethal toxicity: Role of the dopamine and serotonin transporters

✍ Scribed by Yohtaro Numachi; Arihisa Ohara; Motoyasu Yamashita; Setsu Fukushima; Hideaki Kobayashi; Harumi Hata; Hidekazu Watanabe; F. Scott Hall; Klaus-Peter Lesch; Dennis L. Murphy; George R. Uhl; Ichiro Sora

Book ID
113587035
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
597 KB
Volume
572
Category
Article
ISSN
0014-2999

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Methamphetamine (METH) is a drug of abuse that causes deleterious effects to brain monoaminergic systems. These toxic effects are thought to be due to oxidative stress. The pineal hormone, melatonin, has been shown to have neuroprotective effects against toxic quinones and oxidative stress produced