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Methadone metabolism in the rat in vivo : identification of a novel formamide metabolite

โœ Scribed by Abbott, F. S.; Slatter, J. G.; Burton, R.; Il Kang, Gun

Book ID
120585193
Publisher
Informa plc
Year
1985
Tongue
English
Weight
716 KB
Volume
15
Category
Article
ISSN
0049-8254

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Metabolic disposition of pyrazinamide in
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โœ L. W. Whitehouse; B. A. Lodge; A. W. By; B. H. Thomas ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 573 KB

Only limited studies have been reported on the disposition and pharmacokinetics of pyrazinamide (PZA) in both animals and humans. The metabolism of PZA has never been completely elucidated, consequently the metabolites of PZA, pyrazinoic acid (PA), 5-hydroxypyrazinoic acid (SHOPA), and 5-hydroxypyra