Methacrylate-capped fluoro side chain siloxanes: Synthesis, characterization, and their use in the design of oxygen-permeable hydrogels
✍ Scribed by J. Künzler; R. Ozark
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 183 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0021-8995
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✦ Synopsis
chain siloxanes were evaluated for potential use in hydrogels for contact lens application. The preparation of the methacrylate end-capped perfluoro side chain siloxanes was accomplished in two relatively simple synthetic steps. The first step consisted of the acid-catalyzed co-ring opening polymerization of octamethylcyclotetrasiloxane, tetramethylcyclotetrasiloxane, and 1,3-bis-methacryloxybutyltetramethyldisiloxane, followed by a platinum-catalyzed hydrosilation with the tetrafluoro-, octafluoro-, and dodecafluoro-substituted allylic ethers. The incorporation of the terminal [{CF 2 {H] functionality had a dramatic effect on the increased solubility of the fluoro siloxane with hydrophilic monomers. Radical bulk polymerization of the methacrylatecapped fluoro side chain siloxanes with hydrophilic monomers, such as dimethylacrylamide and N-vinyl pyrrolidinone, resulted in transparent hydrogels possessing a wide range of water contents, high oxygen permeability, and a low modulus of elasticity.