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Metformin targets ovarian cancer stem cells in vitro and in vivo

✍ Scribed by J. Shank; R. Buckanovich

Book ID: 113963870
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 76 KB
Volume: 125
Category: Article
ISSN: 0090-8258
DOI: 10.1016/j.ygyno.2011.12.315

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## Abstract A hallmark of cancer cells is an ability to evade apoptosis. Overexpression and/or activating mutations of prosurvival molecules such as the X‐linked inhibitor of apoptosis (XIAP) contribute to this inappropriate cell survival. Our objectives were to investigate the effects of downregul