## Abstract Brief and sublethal ischaemia renders an organ tolerant to subsequent prolonged ischaemia, which is called ischaemic preconditioning (IPC). In regard to the beneficial effects and endogenous mechanisms of renal delayed IPC, few data are available. In this study, we aim at determining re
✦ LIBER ✦
Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-κB activation
✍ Scribed by Moiseeva, Olga; Deschênes-Simard, Xavier; St-Germain, Emmanuelle; Igelmann, Sebastian; Huot, Geneviève; Cadar, Alexandra E.; Bourdeau, Véronique; Pollak, Michael N.; Ferbeyre, Gerardo
- Book ID
- 120083967
- Publisher
- John Wiley and Sons
- Year
- 2013
- Tongue
- English
- Weight
- 774 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1474-9718
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## Abstract ## Objective Suppression of bone destruction is required as part of an effective therapeutic strategy for autoimmune arthritis. Although numerous antirheumatic drugs are in clinical use, little is known about whether they inhibit bone destruction by acting on activated T cells or other