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Metformin impairs the growth of liver kinase B1-intact cervical cancer cells

✍ Scribed by Xuxian Xiao; Qiongqiong He; Changming Lu; Kaitlin D. Werle; Rui-Xun Zhao; Jianfeng Chen; Ben C. Davis; Rutao Cui; Jiyong Liang; Zhi-Xiang Xu

Book ID
118506691
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
893 KB
Volume
127
Category
Article
ISSN
0090-8258

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## Abstract p21‐activated kinase 1 (Pak1), a serine/threonine kinase, has been implicated in cytoskeletal remodelling, cell motility, apoptosis and transformation. However, the role of Pak1 in gastric cancer remains unclear. In this study, we detected Pak1 expression in gastric cancer tissues from