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Metformin and Pathologic Complete Responses to Neoadjuvant Chemotherapy in Diabetic Patients With Breast Cancer

โœ Scribed by Jiralerspong, S.; Palla, S. L.; Giordano, S. H.; Meric-Bernstam, F.; Liedtke, C.; Barnett, C. M.; Hsu, L.; Hung, M.-C.; Hortobagyi, G. N.; Gonzalez-Angulo, A. M.


Book ID
121844877
Publisher
American Society of Clinical Oncology
Year
2009
Tongue
English
Weight
115 KB
Volume
27
Category
Article
ISSN
0732-183X

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Metformin and Pathologic Complete Respon
โœ Jiralerspong, S.; Palla, S. L.; Giordano, S. H.; Meric-Bernstam, F.; Liedtke, C. ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› American Society of Clinical Oncology ๐ŸŒ English โš– 115 KB

## Purpose Population studies have suggested that metformin use in diabetic patients decreases cancer incidence and mortality. Metformin inhibits the growth of cancer cells in vitro and tumors in vivo. However, there is little clinical data to support this. Our purpose was to determine whether met