Metathetic approach towards macrocyclic bis-ethers and in sequence use of barbier reaction and RCM for spirocyclic ethers

✍ Scribed by Sulagna Brahma; Susama Maity; Jayanta K. Ray

• Publisher: Journal of Heterocyclic Chemistry
• Year: 2007
• Tongue: English
• Weight: 355 KB
• Volume: 44
• Category: Article
• ISSN: 0022-152X
• DOI: 10.1002/jhet.5570440105

✦ Synopsis

An efficient method for the synthesis of novel macrocyclic bis-ethers from alizarin and also some new spiro ethers from various substituted ketones by the use of Barbier and ring-closing metathesis (RCM) reactions has been developed.