The morphologic features of mesothelioma occurring in serous fluids, as well as fine-needle aspiration (FNA) of primary tumors, have been extensively described. Descriptions of the FNA findings in metastatic lesions of mesothelioma, however, are limited to single cases. In this report, we illustrate
Metastatic meningioma in fine-needle aspiration (FNA) of the lung: Cytomorphologic finding
โ Scribed by Blaire L. Baisden; Ulrike M. Hamper; Syed Z. Ali
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 475 KB
- Volume
- 20
- Category
- Article
- ISSN
- 8755-1039
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โฆ Synopsis
Pulmonary metastasis of intracranial meningioma is rare. We present the cytomorphologic features of such a tumor in a 71 yr-old woman who was found to have multiple lung nodules 13 years following the resection of an atypical intracranial meningioma. Cytomorphologic features were quite distinct and included hypercellularity with large syncytial groups of monomorphic cells with epithelioid morphologic features, often in perivascular arrangements. Occasional intranuclear cytoplasmic inclusions as well as binucleated cells with wispy cytoplasmic extensions were also noted. Immunoperoxidase studies showed focal positivity for epithelial membrane antigen. The differential diagnosis includes primary or metastatic adenocarcinoma, malignant mesothelioma, and melanoma.
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