✦ LIBER ✦

Metastatic malignant melanoma of unknown primary origin: A study of 30 cases

✍ Scribed by Emmanuel Panagopoulos; Douglas Murray

Publisher: John Wiley and Sons
Year: 1983
Tongue: English
Weight: 256 KB
Volume: 23
Category: Article
ISSN: 0022-4790
DOI: 10.1002/jso.2930230104

No coin nor oath required. For personal study only.

✦ Synopsis

Thirty patients with metastatic malignant melanoma of unknown primary origin treated at Emory University Clinic between 1940 and 1975 are presented. This group represents the 4.4% of all melanomas treated during the same period of time at Emory. Nineteen (63.3%) patients had nodal metastases only, and they were handled by radical lymphadenectomy of the involved area. The remaining 11 patients presented with lung or widespread subcutaneous metastatic disease and treated with biopsy and radiotherapy or chemotherapy. The former group experienced 28.6 % fiveand ten-year actuarial survival while patients with lung metastases succumbed within four months after diagnosis. Spontaneous regression of a typical melanoma skin lesion has been reported in three patients prior to development of metastatic disease.

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