Metastatic breast cancer in males assessment of endocrine therapy
โ Scribed by Jashbhai K. Patel; Takuma Nemoto; Thomas L. Dao
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 277 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0008-543X
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โฆ Synopsis
22 men with metastatic breast cancer were treated with endocrine therapy. All 22 patients were initially treated by bilateral orchiectomy, and objective response was seen in 11 (50%) patients for 15 months. Bilateral adrenalectomy was performed subsequently in 10 patients, and 8 (80%) patients had a mean duration of objective response of 15 months. Five of seven orchiectomy responders and 3 of 3 orchiectomy nonresponders subsequently responded to bilateral adrenalectomy.
๐ SIMILAR VOLUMES
Estrogen receptors in breast tumors were assayed in 55 premenopausal women undergoing bilateral oophorectomy and in 120 postmenopausal women undergoing bilateral adrenalectomy for treatment of metastatic breast cancer. The data show that 20 (60%) of the 32 patients with estrogen receptor-positive (E