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Metastatic breast cancer in males assessment of endocrine therapy

โœ Scribed by Jashbhai K. Patel; Takuma Nemoto; Thomas L. Dao


Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
277 KB
Volume
53
Category
Article
ISSN
0008-543X

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โœฆ Synopsis


22 men with metastatic breast cancer were treated with endocrine therapy. All 22 patients were initially treated by bilateral orchiectomy, and objective response was seen in 11 (50%) patients for 15 months. Bilateral adrenalectomy was performed subsequently in 10 patients, and 8 (80%) patients had a mean duration of objective response of 15 months. Five of seven orchiectomy responders and 3 of 3 orchiectomy nonresponders subsequently responded to bilateral adrenalectomy.


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โœ Thomas L. Dao; Takuma Nemoto ๐Ÿ“‚ Article ๐Ÿ“… 1980 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 384 KB ๐Ÿ‘ 1 views

Estrogen receptors in breast tumors were assayed in 55 premenopausal women undergoing bilateral oophorectomy and in 120 postmenopausal women undergoing bilateral adrenalectomy for treatment of metastatic breast cancer. The data show that 20 (60%) of the 32 patients with estrogen receptor-positive (E