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Metastatic bone disease: pathogenesis and new strategies for treatment

โœ Scribed by Atsumasa Uchida; Hiroki Wakabayashi; Noritaka Okuyama; Atsushi Okamura; Akihiko Matsumine; Katsuyuki Kusuzaki

Publisher
Springer Japan
Year
2004
Tongue
English
Weight
265 KB
Volume
9
Category
Article
ISSN
0949-2658

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## Background Farber Disease is an autosomal-recessively inherited, lysosomal storage disorder caused by acid ceramidase deficiency and associated with distinct clinical phenotypes. Children with significant neurological involvement usually die early in infancy, whereas patients without or only mil