Metastasis: a question of life or death
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Mehlen, Patrick; Puisieux, Alain
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Article
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2006
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Nature Publishing Group
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English
β 535 KB
The metastatic process is highly inefficientvery few of the many cells that migrate from the primary tumour successfully colonize distant sites. One proposed mechanism to explain this inefficiency is provided by the cancer stem cell model, which hypothesizes that micrometastases can only be establis