Metastases detected at the time of diagnosis of primary pediatric extremity osteosarcoma at diagnosis : Imaging features

✍ Scribed by Sue C. Kaste; Charles B. Pratt; Alvida M. Cain; Dana J. Jones-Wallace; Bhaskar N. Rao

• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 93 KB
• Volume: 86
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/(sici)1097-0142(19991015)86:8<1602::aid-cncr31>3.0.co;2-r

✦ Synopsis

BACKGROUND.

The authors performed a retrospective study to estimate the incidence rate of metastatic disease at the time of diagnosis of extremity osteosarcoma (OS), to characterize its pattern of presentation, and to identify factors predictive of survival within a cohort of patients with pulmonary metastatic disease at diagnosis.

METHODS.

From the institutional solid tumor database, the authors identified all patients diagnosed with extremity OS since CT became available at the study institution (1977). The authors recorded patient demographics, the site of primary disease, the histologic subtype of OS, and the presence of metastases at diagnosis.

In those patients with pulmonary metastases at diagnosis, the presence of calcifications, the primary tumor volume, the number of pulmonary lobes with disease, and the number of pulmonary nodules were recorded.