The elimination of difluorocarbene (CF 2 ) from the molecular ions of m-a,a,a-trifluorocresol (MW 162, 1) and p-a, a, a-trifluorocresol (MW 162, 2) upon electron impact have been investigated using a quadrupole ion trap mass spectrometer. This reaction involves a fluorine (F) atom migration from the
Metastable ion study of fluorinated organic compounds. Part 3. α, α, α-trifluoroanisole and α, α, α-trifluorocresols
✍ Scribed by Tamae Yanagisawa; Susumu Tajima; Masaki Iizuka; Seiji Tobita; Motohiro Mitani; Takeo Matsumoto
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 334 KB
- Volume
- 125
- Category
- Article
- ISSN
- 0168-1176
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Regioselective anodic a-monofluorination of oxazolidines 1 derived from a-amino acid was successfully carried out. This is the first example of the successful, direct a-fluorination of protected amino acids. Anodic fluorination of methyl N-acetyl pyroglutamate also provided the corresponding a-fluor
## Abstract Thymine‐α,α,α‐d~3~ (**4**) was synthesized from perdeuterated methyl iodide and pyrimidine‐lithium. Thymidine‐α,α,α‐d~3~ (**8**) was then synthesized by coupling compound **4** with 1α‐chloro‐2‐deoxy‐3,5‐bis(p‐toluoyl)‐α‐D‐ribofuranosyl chloride in the presence of Friedal‐Crafts catalys