Metallothionein protein variants generated in rat liver as a result of DNA and RNA ethylations by the carcinogen diethylnitrosamine

The reversibility of inhibition of RNA a

The reversibility of inhibition of RNA and DNA synthesis induced by aflatoxin in rat liver. A tentative explanation for carcinogenic mechanism

✍ C. Lafarge; C. Frayssinet 📂 Article 📅 1970 🏛 John Wiley and Sons 🌐 French ⚖ 817 KB

## Abstract Aflatoxin is a potent hepatocarcinogen. Biochemically the short‐term action which seems to be the most important is an inhibition of nucleic acid synthesis. Injection of low doses (from 500 to 1,000 μg/kg) made it possible to modulate the different inhibitions induced by aflatoxin. The