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Metallothionein-null mice exhibit reduced tolerance to ultraviolet B injury in vivo

โœ Scribed by W.-H. Wang; L.-F. Li; B.-X. Zhang; X.-Y. Lu


Book ID
108692429
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
220 KB
Volume
29
Category
Article
ISSN
0307-6938

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Tolerance to cadmium hepatotoxicity by m
โœ Peter Coyle; Geralt Niezing; Tanya L. Shelton; Jeffrey C. Philcox; Allan M. Rofe ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 168 KB

The protective role of metallothionein (MT) in Cd-mediated hepatotoxicity was investigated in vivo and in vitro. Following injection of Cd (2 mg/kg, intraperitoneal or subcutaneous) hepatoxicity was significantly greater at 20 h in metallothionein-null (MT -/-) mice, compared with controls (MT+/+).