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Metalloporphyrins as cytochrome P450 models for chlorhexidine metabolite prediction

✍ Scribed by Vinicius Palaretti; Joicy Santamalvina dos Santos; Débora Fernandes Costa Guedes; Luiz Alberto Beraldo de Moraes; Marilda das Dores Assis

Book ID
119190978
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
637 KB
Volume
447-448
Category
Article
ISSN
0926-860X

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## Abstract Cytochrome P450 (CYP) is an important drug‐metabolizing enzyme family. Different CYPs often have different substrate preferences. In addition, one drug molecule may be preferentially metabolized by one or more CYP enzymes. Therefore, the classification and prediction of substrate specif