The protons at 3-positions of diazepam 4-oxide and nordiazepam 4-oxide underwent an efficient deuterium exchange via keto-enol tautomerism in deuterated alkaline methanol. The 3-dideuterated 4-oxides were each used as a starting material to synthesize 3-monodeuterated oxazepam and its 3-acetate, 3mo
Metalation of diazepam and use of the resulting carbanion intermediate in a new synthesis of 3-substituted diazepam derivatives
โ Scribed by Reitter, Barbara E.; Sachdeva, Yesh P.; Wolfe, James F.
- Book ID
- 118210240
- Publisher
- American Chemical Society
- Year
- 1981
- Tongue
- English
- Weight
- 670 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0022-3263
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