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Metal-Mediated Oxidative Cross-Coupling of Terminal Alkynes: A Promising Strategy for Alkyne Synthesis

✍ Scribed by Prof. Dr. Zhihui Shao; Fangzhi Peng


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
239 KB
Volume
49
Category
Article
ISSN
0044-8249

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Zirconium-Mediated Cross-Coupling of Ter
✍ José Barluenga; Félix Rodríguez; Lucía Álvarez-Rodrigo; Francisco J. Fañanás 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 167 KB 👁 2 views

## Abstract A diastereoselective synthesis of 1,3‐butadiene or cyclobutene derivatives by a zirconium‐mediated reaction of alkenyllithium compounds and vinyl bromides is reported. The key steps involve the generation of zirconocene–alkyne complexes from haloalkenes and subsequent coupling with alke