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Metal ions dramatically enhance the enantioselectivity for lipase-catalysed reactions in organic solvents

✍ Scribed by Okamoto, Takashi; Yasuhito, Ebara; Ueji, Shin-ichi


Book ID
119947988
Publisher
Royal Society of Chemistry
Year
2006
Tongue
English
Weight
153 KB
Volume
4
Category
Article
ISSN
1477-0520

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Enhancement of enantioselectivity and re
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## Abstract Lipase‐catalyzed enantioselective esterification between (__R__,__S__)‐ketoprofen and alkanediol in organic solvents was developed to produce (__S__)‐ketoprofen hydroxyalkyl esters. The acyl acceptor of 1,6‐hexanediol for the resolution of (__R__,__S__)‐ketoprofen yielded only the enant