Metal ion-dependent binding of gastrin to albumin
β Scribed by Richard J. Mann; Geoffrey J. Howlett; Graham S. Baldwin
- Book ID
- 115708738
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 936 KB
- Volume
- 291
- Category
- Article
- ISSN
- 0003-9861
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## Abstract The fully active gastrin and CCK analogues [Nle^15^]βgastrinβ 17 and [Nle, Thr]βCCKβ9 were analysed for their Ca^2+^ and Tb^3+^ affinities in various membrane mimetic conditions. In TFE both gastrin and CCK exhibited high affinities for calcium and terbium. At saturation level identical
The binding of cupric ions to bovine serum albumin was investigated by using a cupric-ion-specific electrode. When using a modified form of the Scatchard equation, it was determined that there are at least two classes of binding sites on bovine serum albumin for cupric ions. One class has three bind