𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Metal-Free Triazole Formation as a Tool for Bioconjugation

✍ Scribed by Sander S. van Berkel; A. (Ton) J. Dirks; Marjoke F. Debets; Floris L. van Delft; Jeroen J. L. M. Cornelissen; Roeland J. M. Nolte; Floris P. J. T. Rutjes

Book ID
101823129
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
189 KB
Volume
8
Category
Article
ISSN
1439-4227

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Living Radical Polymerization as a Tool
Living Radical Polymerization as a Tool for the Synthesis of Polymer-Protein/Peptide Bioconjugates
✍ Julien Nicolas; Giuseppe Mantovani; David M. Haddleton 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 907 KB

## Abstract Combinations of synthetic and natural macromolecules offer a route to new functional materials. While biological and polymer chemistry may not be natural bedfellows, many researchers are focusing their attention on the benefits of combining these fields. Recent advances in living radica

Application of Metal-Free Triazole Forma
Application of Metal-Free Triazole Formation in the Synthesis of Cyclic RGD–DTPA Conjugates
✍ Sander S. van Berkel; A. (Ton) J. Dirks; Silvie A. Meeuwissen; Dennis L. L. Ping 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 501 KB

## Abstract The tandem 1,3‐dipolar cycloaddition‐retro‐Diels–Alder (tandem crDA) reaction is presented as a versatile method for metal‐free chemoselective conjugation of a DTPA radiolabel to __N__‐δ‐azido‐cyclo(‐Arg‐Gly‐Asp‐d‐Phe‐Orn‐) via oxanorbornadiene derivatives. To this end, the behavior of