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Metal-Catalyzed Regiodivergent Cyclization of γ-Allenols: Tetrahydrofurans versus Oxepanes

✍ Scribed by Benito Alcaide; Pedro Almendros; Teresa Martínez del Campo


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
122 KB
Volume
119
Category
Article
ISSN
0044-8249

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Metal-Catalyzed Cyclization of β- and γ-
✍ Benito Alcaide; Pedro Almendros; Teresa Martínez del Campo; Elena Soriano; José  📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 499 KB

## Abstract Regiocontrolled metal‐catalyzed preparations of enantiopure dihydropyrans and tetrahydrooxepines have been synthesized starting from β‐ and γ‐allenols derived from D‐glyceraldehyde. The Pd^II^‐catalyzed cyclizative coupling reactions of β‐allenols **1 a** and **1 b** with allyl bromide