๐”– Bobbio Scriptorium
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Metagenomic approaches to exploit the biotechnological potential of the microbial consortia of marine sponges

โœ Scribed by Jonathan Kennedy; Julian R. Marchesi; Alan D. W. Dobson


Publisher
Springer
Year
2007
Tongue
English
Weight
301 KB
Volume
75
Category
Article
ISSN
1432-0614

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Fascaplysin 1, an antimicrobial and cytotoxic red pigment of the marine sponge Fascaplysinopsis sp.. has been synthesized in five steps from tryptamine 2 in 44% overall yield. The key steps in the synthesis are: (a) dehydrogenation of the dihydro-13-.carboline intermediate 4 simultaneously with its