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Metachronous spread of parathyroid carcinoma to a retropharyngeal lymph node

✍ Scribed by Justin B. Rufener; James I. Cohen

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
72 KB
Volume
25
Category
Article
ISSN
1043-3074

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✦ Synopsis

Background:

Parathyroid carcinoma is rare and accounts for approximately 1% of patients with hyperparathyroidism. it is a slowly progressive disease with frequent recurrence and high incidence of local metastasis. because of the rarity of this tumor, little is known about the pattern of lymph node metastasis.

Methods:

A case of retropharyngeal lymph node metastasis found 2 years after initial diagnosis of parathyroid carcinoma is presented and discussed.

Results:

A 67-year-old man initially was seen with asymptomatic hypercalcemia, and a 1.7-cm mass was removed along with the left hemithyroid. the mass was found to be parathyroid carcinoma. serum calcium was again elevated 1 year later, and left neck lymph node dissection revealed an upper jugular lymph node containing parathyroid carcinoma. the patient continued to have an elevated serum calcium level, and a retropharyngeal lymph node was found by mri and removed the following year. the patient is now without evidence of hyperparathyroidism or recurrent disease at 2-year follow-up.

Conclusions:

Persistent parathyroid carcinoma is often a clinical challenge because of the difficulty in localizing recurrent tumor. retropharyngeal lymph nodes should be considered as a possible site of metastasis in patients with parathyroid carcinoma.

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